⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100154 | 0.76 | — | — | |
| SCHEMBL5154280 | 0.76 | — | — | |
| SCHEMBL10532548 | 0.74 | PNMT (0.32) | — | |
| SCHEMBL13568091 | 0.74 | TSHR (0.34) | — | |
| SCHEMBL4836303 | 0.74 | KDM4E (0.34) | — | |
| SCHEMBL24552915 | 0.73 | — | — | |
| SCHEMBL12504670 | 0.73 | — | — | |
| SCHEMBL24553580 | 0.73 | — | — | |
| SCHEMBL7412703 | 0.73 | — | — | |
| SCHEMBL12969603 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143746-B | Compound for preventing nerve injury and protecting nerve, its preparation method, medicinal products and application | 健裕生技股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| CN-113877557-B | Method for synthesizing olanzapine intermediate by one-pot joint and special solid base catalyst | 山东安舜制药有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-11987566-B2 | Nerve damage preventing and nerve protecting compounds, preparation method thereof, pharmaceutical composition thereof, and their use | GENHEALTH PHARMA CO., LTD. (TW) | 2024-05-21 | — | — | US | claimed |
| EP-4230622-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | Genhealth Pharma Co., Ltd. (TW) | 2023-08-23 | — | — | EP | claimed |
| US-20230242501-A1 | NERVE DAMAGE PREVENTING AND NERVE PROTECTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND THEIR USE | GENHEALTH PHARMA CO., LTD. (TW) | 2023-08-03 | — | — | US | claimed |
| CN-116143746-A | Compound for preventing nerve injury and protecting nerve, its preparation method, medicinal products and application | 健裕生技股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113877557-A | Method for synthesizing olanzapine intermediate by one-pot continuous feeding and special solid base catalyst | 山东安舜制药有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-102225941-B | Preparation method of antipsychotic drug olanzapine | NINGBO RENJIAN PHARMACEUTICAL CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-102225941-A | Preparation method of antipsychotic drug olanzapine | NINGBO RENJIAN PHARMACEUTICAL CO LTD | 2011-10-26 | — | — | CN | claimed |
| US-RE40033-E1 | Process for preparing 2-methyl-thieno-benzodiazepine | ELI LILLY AND COMPANY (US) | 2008-01-22 | — | — | US | claimed |
| US-6008216-A | CHEMICAL SYNTHESIS OF ANTIPSYCHOTIC DRUGS FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM, SERIOUS MENTAL CONDITIONS SUCH AS PSYCHOSIS, SCHIZOPHRENIA AND SCHIZOPHRENIFORM ILLNESSES | ELI LILLY AND COMPANY AND LIMITED (GB) | 1999-12-28 | — | — | US | claimed |
| EP-4725493-A2 | POLYCYCLIC COMPOUNDS FOR INHIBITING RNA HELICASE DHX33 AND USE THEREOF | Shenzhen Keye Life Technologies, Co., Ltd. (CN) | 2026-04-15 | — | — | EP | disclosed |
| EP-3581195-B1 | ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-10-01 | — | — | EP | disclosed |
| EP-3492473-B1 | HAPTENS OF OLANZAPINE | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-30 | — | — | EP | disclosed |
| CN-116143746-B | Compound for preventing nerve injury and protecting nerve, its preparation method, medicinal products and application | 健裕生技股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| US-5229382-A | Treating disorders of the central nervous system including psychosis, acute mania, anxiety, or schizophrenia | LILLY INDUSTRIES LIMITED (GB) | 1993-07-20 | — | — | US | disclosed |
| EP-0454436-A1 | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1991-10-30 | — | — | EP | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0224140-A1 | Thienyl urea derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |