Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244592 | 0.95 | ALDH1A1 (0.42) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL14441603 | 0.95 | TRIM24 (0.42) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL13334321 | 0.92 | ALDH1A1 (0.41) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL3438361 | 0.92 | ALDH1A1 (0.41) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL4866556 | 0.92 | ALDH1A1 (0.41) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL10514312 | 0.90 | TRIM24 (0.41) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL16512839 | 0.90 | ALDH1A1 (0.35) | MAPTTRIM24TRIM33ALDH1A1MAPK1 | |
| SCHEMBL11593525 | 0.90 | ALDH1A1 (0.35) | MAPTTRIM24TRIM33ALDH1A1MAPK1 | |
| SCHEMBL11330899 | 0.87 | TRIM24 (0.48) | MAPTTRIM24TRIM33THRBALDH1A1 | |
| SCHEMBL29989395 | 0.86 | TRIM24 (0.53) | MAPTTRIM24TRIM33THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089010-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |