Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965035 | 0.81 | SMN1; SMN2 (0.44) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8554367 | 0.79 | SIRT2 (0.47) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10094744 | 0.79 | PPARA (0.46) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3256199 | 0.78 | — | — | |
| SCHEMBL507580 | 0.75 | SIRT2 (0.45) | SIRT2SMN1; SMN2 | |
| SCHEMBL19348179 | 0.75 | MAPT (0.40) | MAPTCYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL9736792 | 0.74 | — | — | |
| SCHEMBL2608946 | 0.72 | MAPT (0.44) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL475088 | 0.72 | HTR1A (0.44) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16373731 | 0.71 | MAPT (0.43) | SIRT2MAPTCYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096094-A1 | BICYCLOR[2.2.1]HEPT-7-YLAMINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096094-A1 | BICYCLOR[2.2.1]HEPT-7-YLAMINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |