Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741995 | 1.00 | CHRM1 (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL523789 | 0.93 | CHRM2 (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL523790 | 0.93 | CHRM2 (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| Bromide SCHEMBL1179587 | 0.92 | CHRM2 (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| Bromide SCHEMBL1179592 | 0.92 | CHRM2 (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL4743333 | 0.92 | LMNA (0.33) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL4741478 | 0.91 | CYP19A1 (0.37) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL4741480 | 0.91 | CYP19A1 (0.37) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL524178 | 0.90 | CHRM2 (0.36) | CHRM1CHRM2KCNH2LMNASLC6A3 | |
| SCHEMBL4743343 | 0.90 | CHRM2 (0.36) | CHRM1CHRM2KCNH2LMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |