SCHEMBL4742189

SCHEMBL4742189

NC(=O)c1nn(-c2ccccc2)c(O)c1N=Nc1ncnn1-c1ncccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.34
CASP1 P29466 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CCNA2 P20248 3/20 0.33
CDK2 P24941 3/20 0.33
CCNA1 P78396 3/20 0.33
AURKA O14965 2/20 0.33
SCN9A Q15858 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
PKM P14618 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
KAT2B Q92831 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742166 0.78 KMT2A (0.37) KMT2AALDH1A1LMNAKDM4ECCNA2
SCHEMBL4742658 0.74 LDHA (0.39) KMT2AALDH1A1LMNAMAPTKDM4E
SCHEMBL10560088 0.74 KMT2A (0.55) KMT2AALDH1A1LMNAMAPTCASP1
SCHEMBL4742165 0.66 SMN1; SMN2 (0.37) KMT2AALDH1A1MAPTKDM4EMEN1
SCHEMBL4742191 0.66 CYP1A2 (0.44) KMT2AALDH1A1LMNAMAPTMEN1
SCHEMBL13915857 0.65 MAPK1 (0.48) KMT2AALDH1A1MAPTKDM4EMEN1
SCHEMBL14500838 0.65 MAPK1 (0.48) KMT2AALDH1A1MAPTKDM4EMEN1
SCHEMBL11564027 0.64 KMT2A (0.55) KMT2AALDH1A1LMNAMAPTCASP1
SCHEMBL19551408 0.63 RIPK2 (0.50) KMT2AALDH1A1LMNAKDM4EMEN1
SCHEMBL16478904 0.61 MAPT (0.49) KMT2AALDH1A1LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed