SCHEMBL4742313

[C-]#[N+]c1cnn(-c2nc(-n3ncc(C#N)c3/N=N/c3c(C)c(C#N)c(=O)n(C)c3O)nc(-n3ncc(C#N)c3/N=N/c3c(C)c(C#N)c(=O)n(C)c3O)n2)c1/N=N/c1c(C)c([N+]#[C-])c(=O)n(C)c1O

nearest known ligand 0.33

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	3/20	0.33

▸	MAPT	P10636	3/20	0.33

▸	KMT2A	Q03164	3/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	KDM4E	B2RXH2	2/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4781146	0.88	MAPT (0.40)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL4743198	0.80	MAPT (0.38)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL4742259	0.80	MAPT (0.38)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL4742653	0.74	SMN1; SMN2 (0.33)	MAPTSMN1; SMN2
SCHEMBL4742314	0.73	MAPT (0.39)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL4742267	0.72	MEN1 (0.33)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2
SCHEMBL12910534	0.69	—	—
SCHEMBL12052322	0.68	—	—
SCHEMBL12910550	0.68	—	—
SCHEMBL1613303	0.68	SMN1; SMN2 (0.41)	MEN1MAPTKMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8177861-B2	AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition	FUJIFILM CORPORATION (JP)	2012-05-15	—	—	US	disclosed
US-20110021764-A1	AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION	FUJIFILM CORPORATION (JP)	2011-01-27	—	—	US	disclosed