SCHEMBL4742357

SCHEMBL4742357

CS(=O)(=O)Nc1nc(N2CCOCC2)sc1/N=N/c1c(C#N)cnn1-c1nccs1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
SCN9A Q15858 3/20 0.31
TBK1 Q9UHD2 1/20 0.30
PIK3CD O00329 2/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742332 0.68 ALDH1A1 (0.35) MEN1POLBTSHRKMT2AHTT
SCHEMBL4742334 0.66 CSNK2A1 (0.35) MEN1POLBTSHRKMT2AHTT
SCHEMBL10101842 0.63 NPC1 (0.31)
SCHEMBL10101888 0.62 IKBKB (0.41) PIK3CAMTORPIK3CGMEN1USP2
SCHEMBL10102088 0.61 HTT (0.36) PIK3CAMEN1USP2POLBTSHR
SCHEMBL10101823 0.61 HTT (0.36) PIK3CAMEN1USP2POLBTSHR
SCHEMBL10101894 0.61 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL10101889 0.61 MEN1 (0.38) PIK3CAMEN1USP2POLBTSHR
SCHEMBL10102113 0.61 TSHR (0.37) MEN1USP2POLBTSHRKMT2A
SCHEMBL10101958 0.61 TSHR (0.37) MEN1USP2POLBTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed