Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 13/20 | 0.58 |
| ▸ | APOB | P04114 | 10/20 | 0.58 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213608 | 0.91 | MTTP (0.60) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8507709 | 0.91 | MTTP (0.58) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8213404 | 0.91 | MTTP (0.58) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8208665 | 0.90 | MTTP (0.57) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8208323 | 0.90 | APOB (0.58) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8208329 | 0.90 | MTTP (0.57) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8506927 | 0.89 | MTTP (0.59) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8210354 | 0.89 | MTTP (0.56) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8200984 | 0.89 | APOB (0.62) | MTTPAPOBSMOKDM4EGAA | |
| SCHEMBL8211067 | 0.89 | MTTP (0.61) | MTTPAPOBSMOKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996564-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | Pfizer Products Incorporated (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007105050-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2006032987-A1 | INDOLINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF ARTERIOSCLEROSIS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |