SCHEMBL4742436

SCHEMBL4742436

Cc1cc(N2CCOCC2)c(C)cc1/N=N/c1c(C#N)cnn1-c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TSHR P16473 2/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
HTT P42858 3/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LRRK2 Q5S007 1/20 0.36
METAP1 P53582 1/20 0.35
ROCK2 O75116 1/20 0.35
ROCK1 Q13464 1/20 0.35
CDC42BPB Q9Y5S2 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742494 0.70 KCNH2 (0.39) MEN1KMT2AALDH1A1MAPTATM
SCHEMBL10102088 0.69 HTT (0.36) MEN1KMT2ATSHRUSP2POLB
SCHEMBL10101823 0.69 HTT (0.36) MEN1KMT2ATSHRUSP2POLB
SCHEMBL4742169 0.69 MAPT (0.42) MEN1KMT2ATSHRHTTALDH1A1
SCHEMBL10101979 0.67 ALDH1A1 (0.37) MEN1KMT2ATSHRPOLBHTT
SCHEMBL10101919 0.67 NPC1 (0.34) MEN1KMT2ATSHRALDH1A1KDM4E
SCHEMBL10101914 0.66 ALDH1A1 (0.38) MEN1KMT2ATSHRPOLBHTT
SCHEMBL4742197 0.66 SMN1; SMN2 (0.39) MEN1KMT2ATSHRUSP2POLB
SCHEMBL4742332 0.66 ALDH1A1 (0.35) MEN1KMT2ATSHRPOLBHTT
SCHEMBL10101954 0.66 PLAUR (0.35) MEN1KMT2AHTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed