SCHEMBL4742460

SCHEMBL4742460

Oc1cccc(/C=C/c2cc(O)cc(O)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 4/20 1.00
PTGS1 P23219 3/20 0.70
PTGS2 P35354 2/20 0.70
ABL1 P00519 2/20 0.66
BCR P11274 2/20 0.66
TTR P02766 3/20 0.63
PELI1 Q96FA3 2/20 0.62
CCNB2 O95067 1/20 0.61
CDK1 P06493 1/20 0.61
CDK4 P11802 1/20 0.61
CCNB1 P14635 1/20 0.61
CCND1 P24385 1/20 0.61
CCNB3 Q8WWL7 1/20 0.61
KDM4E B2RXH2 3/20 0.60
MEN1 O00255 3/20 0.60
ALDH1A1 P00352 3/20 0.60
LMNA P02545 3/20 0.60
TP53 P04637 3/20 0.60
CYP1A2 P05177 3/20 0.60
CYP3A4 P08684 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742462 1.00 LCK (1.00) LCKPTGS1PTGS2ABL1BCR
SCHEMBL30194225 1.00 LCK (1.00) LCKPTGS1PTGS2ABL1BCR
SCHEMBL23754269 1.00 LCK (1.00) LCKPTGS1PTGS2ABL1BCR
SCHEMBL23754267 1.00 LCK (1.00) LCKPTGS1PTGS2ABL1BCR
SCHEMBL3392045 0.95 LCK (0.91) LCKPTGS1PTGS2ABL1BCR
SCHEMBL13338339 0.93 LCK (0.86) LCKPTGS1PTGS2ABL1BCR
SCHEMBL2512336 0.93 LCK (0.86) LCKPTGS1PTGS2ABL1BCR
SCHEMBL2512334 0.93 LCK (0.86) LCKPTGS1PTGS2ABL1BCR
(E)-3-Stilbenol SCHEMBL5489745 0.86 LCK (0.75) LCKPTGS1PTGS2ABL1BCR
(E)-3-Stilbenol SCHEMBL113159 0.86 LCK (0.75) LCKPTGS1PTGS2ABL1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723834-B1 Low melting and low viscosity thermoset matrix resins from the Z configuration of polyhydroxy stilbenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-07-28 US claimed
US-11118002-B1 Low melting and low viscosity thermoset matrix resins from the Z configuration of polyhydroxy stilbenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-09-14 US disclosed
WO-2021160139-A1 9,10-DIHYDROPHENANTHRENE COMPOUNDS AND USE THEREOF IN TREATMENT OF LIVER INJURY 中国科学院上海药物研究所 2021-08-19 WO disclosed
US-10723834-B1 Low melting and low viscosity thermoset matrix resins from the Z configuration of polyhydroxy stilbenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-07-28 US disclosed
EP-1448232-B1 ANTI-PROLIFERATIVE COMPOSITION NUTRICIA NV (NL) 2014-07-02 EP disclosed
WO-2008103346-A1 COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS PROFECTUS BIOSCIENCES, INC. (US) 2008-08-28 WO disclosed
US-20040259815-A1 Anti-proliferative composition GENERAL NUTRITION INVESTMENT COMPANY 2004-12-23 US disclosed
EP-1207907-B1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS, AND METHODS THEREFOR UNIV MARYLAND BIOTECH INST (US) 2004-11-03 EP disclosed
EP-1448232-A1 ANTI-PROLIFERATIVE COMPOSITION N.V. Nutricia (NL) 2004-08-25 EP disclosed
WO-2003043658-A1 ANTI-PROLIFERATIVE COMPOSITION N.V. NUTRICIA (NL) 2003-05-30 WO disclosed
EP-0464461-B1 Stilbensynthase gene of grapevine BAYER AG (DE) 2000-11-15 EP disclosed
US-6020129-A Stilbene synthase gene BAYER AKTIENGESELLSCHAFT (DE) 2000-02-01 US disclosed
US-5985647-A Stilbene synthase gene BAYER AKTIENGESELLSCHAFT (DE) 1999-11-16 US disclosed
US-5834268-A PRODUCING PLANTS WITH INCREASED RESISTANCE TO PESTS, INSERTING GENE FOR PRODUCTION OF STILBENES BAYER AKTIENGESELLSCHAFT (DE) 1998-11-10 US disclosed
US-5689047-A PEST RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-5689046-A PEST RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-5500367-A Stilbene synthase genes from grapevine BAYER AKTIENGESELLSCHAFT (DE) 1996-03-19 US disclosed
EP-0309862-B1 STILBENE SYNTHASE GENE BAYER AG (DE) 1992-08-12 EP disclosed
EP-0464461-A2 Stilbensynthase gene of grapevine BAYER AG (DE) 1992-01-08 EP disclosed
EP-0309862-A1 Stilbene synthase gene BAYER AG (DE) 1989-04-05 EP disclosed