Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.75 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.61 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | CDK4 | P11802 | 1/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.61 |
| ▸ | CCND1 | P24385 | 1/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | BCR | P11274 | 1/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (E)-3-Stilbenol SCHEMBL113158 | 1.00 | LCK (0.75) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL113159 | 1.00 | LCK (0.75) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL30364828 | 1.00 | LCK (0.75) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419822 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419840 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419842 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419843 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419816 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| (E)-3-Stilbenol SCHEMBL9419819 | 0.98 | LCK (0.72) | LCKCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL13338339 | 0.93 | LCK (0.86) | LCKCCNB2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223747-B2 | Halocombstatins and methods of synthesis thereof | ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050176688-A1 | Halocombstatins and methods of synthesis thereof | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176688-A1 | Halocombstatins and methods of synthesis thereof | TUBB3, TUBB8B, TUBB8 | LCK 3249/4885CCNB2 542/4885CDK1 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.