SCHEMBL4742492

SCHEMBL4742492

CC(=O)Nc1ccccc1Oc1c(Cl)cc(/N=N/c2c(C#N)cnn2-c2ncccn2)cc1C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.34
STK3 Q13188 1/20 0.34
ROCK2 O75116 2/20 0.33
EGFR P00533 1/20 0.32
JAK2 O60674 2/20 0.32
JAK1 P23458 2/20 0.32
TYK2 P29597 2/20 0.32
JAK3 P52333 2/20 0.32
PIN1 Q13526 1/20 0.32
CSF1R P07333 1/20 0.32
MAP2K1 Q02750 1/20 0.32
PYGL P06737 1/20 0.32
PYGM P11217 1/20 0.32
MAPK3 P27361 1/20 0.32
STK4 Q13043 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742480 0.78 ALDH1A1 (0.39) STK3MAP2K1STK4KDM4ENPSR1
SCHEMBL13943118 0.71 SMN1; SMN2 (0.41) MAP2K1KDM4EKMT2ALMNA
SCHEMBL13943117 0.71 SMN1; SMN2 (0.36) ARMAP2K1KDM4EKMT2ALMNA
SCHEMBL4742945 0.71 IRAK4 (0.38) KDM4EMEN1KMT2A
SCHEMBL4780174 0.69 GFER (0.41) KDM4EMEN1KMT2ARXFP1
SCHEMBL4742455 0.69 KCNH2 (0.36) STK4MEN1KMT2ANPSR1
SCHEMBL4742957 0.69 GFER (0.40) KDM4EMEN1KMT2A
SCHEMBL4742942 0.69 HTT (0.36) KDM4EMEN1KMT2A
SCHEMBL4742442 0.68 MAPT (0.35) KDM4EMEN1KMT2ANPSR1LMNA
SCHEMBL4742461 0.68 AR (0.34) ARKDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed