SCHEMBL4742499

SCHEMBL4742499

CC(=O)Nc1cc(/N=N/c2c(C#N)cnn2-c2ccccn2)c2c(c1O)CCC(=O)N2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
PKM P14618 1/20 0.32
CRBN Q96SW2 1/20 0.32
CSNK2A1 P68400 3/20 0.31
GSK3B P49841 1/20 0.31
HIPK2 Q9H2X6 1/20 0.31
KIT P10721 2/20 0.31
FLT3 P36888 2/20 0.31
SPR P35270 1/20 0.30
OGA O60502 1/20 0.30
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CCNA1 P78396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17089142 0.71
SCHEMBL12506903 0.68 MALT1 (0.40) FFAR4
SCHEMBL4742439 0.67 ALDH1A1 (0.38) KDM4EALDH1A1GAAHTTSMN1; SMN2
SCHEMBL4742442 0.67 MAPT (0.35) KDM4EALDH1A1HTTSMN1; SMN2CSNK2A1
SCHEMBL12507143 0.67 PHLPP2 (0.36) FFAR4CSNK2A1
SCHEMBL4742455 0.66 KCNH2 (0.36)
SCHEMBL12507146 0.66 PHLPP2 (0.36) KDM4EFFAR4
SCHEMBL12507016 0.66 MALT1 (0.39)
SCHEMBL12507233 0.66 MALT1 (0.39) ALDH1A1GAASMN1; SMN2PKM
SCHEMBL1085976 0.66 MAPK14 (0.39) KDM4EALDH1A1SMN1; SMN2PKMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed