SCHEMBL4742553

SCHEMBL4742553

N#Cc1cnn(-c2ccccn2)c1N=Nc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.34
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33
GRIA1 P42261 1/20 0.32
GRIA3 P42263 1/20 0.32
PDE4D Q08499 1/20 0.32
PLAUR Q03405 1/20 0.32
TP53 P04637 2/20 0.32
MDM2 Q00987 1/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
CSNK2A1 P68400 1/20 0.31
PKM P14618 1/20 0.31
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742576 0.90 SMN1; SMN2 (0.36) DPP4SMN1; SMN2MAPTPTGS1PTGS2
SCHEMBL4742643 0.87 SMN1; SMN2 (0.36) DPP4SMN1; SMN2MAPTPTGS1PTGS2
SCHEMBL4742612 0.83 FFAR4 (0.36) DPP4FFAR4SMN1; SMN2MAPTPTGS1
SCHEMBL4742197 0.80 SMN1; SMN2 (0.39) DPP4FFAR4SMN1; SMN2MAPTTP53
SCHEMBL13996972 0.80 MAPT (0.35) DPP4MAPTTP53MDM2HPGD
SCHEMBL13996969 0.79 NPSR1 (0.35) DPP4FFAR4MAPTTP53HPGD
SCHEMBL4742653 0.79 SMN1; SMN2 (0.33) SMN1; SMN2MAPTPTGS1PTGS2TP53
SCHEMBL4742314 0.78 MAPT (0.39) DPP4FFAR4SMN1; SMN2MAPTTP53
SCHEMBL4742169 0.78 MAPT (0.42) FFAR4SMN1; SMN2MAPTTP53NPC1
SCHEMBL13996968 0.74 MAPT (0.35) DPP4SMN1; SMN2MAPTHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20080310293-A1 OPTICAL INFORMATION RECORDING MEDIUM AND METHOD OF RECORDING INFORMATION FUJIFILM CORPORATION (JP) 2008-12-18 US disclosed
EP-1998329-A2 Optical information recording medium and method of recording information Fujifilm Corporation (JP) 2008-12-03 EP disclosed
US-20080081285-A1 OPTICAL INFORMATION RECORDING MEDUM AND AZO-METAL COMPLEX DYE FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed