SCHEMBL4742576

SCHEMBL4742576

N#Cc1cnn(-c2ncccn2)c1N=Nc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 3/20 0.35
DPP4 P27487 2/20 0.35
PTGS1 P23219 2/20 0.34
PTGS2 P35354 2/20 0.34
TP53 P04637 1/20 0.33
MDM2 Q00987 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 4/20 0.32
GFER P55789 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
XDH P47989 1/20 0.32
GRIA1 P42261 1/20 0.31
GRIA3 P42263 1/20 0.31
PDE4D Q08499 1/20 0.31
NPC1 O15118 1/20 0.31
MITF O75030 1/20 0.31
S1PR4 O95977 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4742643 0.97 SMN1; SMN2 (0.36) SMN1; SMN2MAPTDPP4PTGS1PTGS2
SCHEMBL4742553 0.90 DPP4 (0.37) SMN1; SMN2MAPTDPP4PTGS1PTGS2
SCHEMBL4742653 0.84 SMN1; SMN2 (0.33) SMN1; SMN2MAPTPTGS1PTGS2TP53
SCHEMBL4742563 0.82 MAPT (0.36) SMN1; SMN2MAPTDPP4PTGS1PTGS2
SCHEMBL4743196 0.81 SMN1; SMN2 (0.38) SMN1; SMN2DPP4PTGS1PTGS2ALDH1A1
SCHEMBL4742162 0.80 SMN1; SMN2 (0.39) SMN1; SMN2DPP4PTGS1PTGS2ALDH1A1
SCHEMBL4742592 0.79 PTGS1 (0.35) SMN1; SMN2MAPTPTGS1PTGS2ALDH1A1
SCHEMBL4742166 0.79 KMT2A (0.37) SMN1; SMN2DPP4PTGS1PTGS2ALDH1A1
SCHEMBL4742303 0.78 DPP4 (0.36) SMN1; SMN2MAPTDPP4PTGS1PTGS2
SCHEMBL4742164 0.76 PTGS1 (0.38) SMN1; SMN2MAPTDPP4PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed