Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150774 | 0.85 | DHODH (0.46) | SMN1; SMN2MAPTGAAATMMEN1 | |
| SCHEMBL395325 | 0.84 | DHODH (0.46) | SMN1; SMN2MAPTGAATP53ALDH1A1 | |
| SCHEMBL11631229 | 0.83 | MAPT (0.50) | SMN1; SMN2MAPTGAAMEN1KMT2A | |
| SCHEMBL5768187 | 0.81 | MEN1 (0.58) | SMN1; SMN2MAPTGAATP53RXFP1 | |
| SCHEMBL4742578 | 0.80 | POLB (0.46) | SMN1; SMN2MAPTALOX12MEN1KMT2A | |
| SCHEMBL846105 | 0.78 | MAPT (0.45) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4742564 | 0.78 | NPSR1 (0.72) | SMN1; SMN2MAPTGAAALOX12ATM | |
| SCHEMBL4740015 | 0.78 | POLB (0.44) | SMN1; SMN2GAAATMKMT2AALDH1A1 | |
| SCHEMBL2650764 | 0.77 | MEN1 (0.44) | MAPTTP53RXFP1MEN1KMT2A | |
| SCHEMBL2654421 | 0.77 | EPHX2 (0.42) | SMN1; SMN2GAATP53RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |