Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395325 | 0.83 | DHODH (0.46) | NPSR1NPC1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL11631229 | 0.82 | MAPT (0.50) | KMT2AMEN1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL4150774 | 0.82 | DHODH (0.46) | KMT2AMEN1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL11779893 | 0.81 | GLO1 (0.58) | KMT2AMEN1ALDH1A1MAPK1CACNA1C | |
| SCHEMBL4837457 | 0.81 | SMN1; SMN2 (0.46) | KMT2AMEN1HPGDPKMSMN1; SMN2 | |
| SCHEMBL4742568 | 0.80 | SMN1; SMN2 (0.48) | POLBKMT2AMEN1HPGDNPSR1 | |
| SCHEMBL4742571 | 0.78 | DHODH (0.64) | KMT2AMEN1HPGDHSP90AA1NPSR1 | |
| SCHEMBL4739345 | 0.78 | MAPT (0.47) | POLBKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL11776081 | 0.77 | GLO1 (0.56) | KMT2AMEN1ALDH1A1MAPK1CACNA1C | |
| SCHEMBL5046716 | 0.76 | DHODH (0.58) | POLBKMT2AMEN1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093940-A1 | QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |