Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | FABP2 | P12104 | 2/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473988 | 0.83 | TSHR (0.46) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL27486196 | 0.83 | ESR1 (0.50) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL29613223 | 0.82 | CYP1A2 (0.60) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL305060 | 0.82 | CYP1A2 (0.60) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL16753453 | 0.82 | CYP1A2 (0.60) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL1625391 | 0.80 | MEN1 (0.54) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL11625903 | 0.80 | KMT2A (0.54) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL697244 | 0.80 | MAP4K4 (0.55) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL568903 | 0.78 | KMT2A (0.58) | MEN1KMT2APPARACYP1A2CYP2C19 | |
| SCHEMBL3557871 | 0.78 | KMT2A (0.52) | MEN1KMT2APPARACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090357-A2 | N, N; -SUBSTITUTED PIPERAZINES BINDING TO MELANOCORTIN RECEPTOR | PALATIN TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | WO | disclosed |