SCHEMBL305060

SCHEMBL305060

CC(Cl)(C(=O)O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.60
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP2C19 P33261 3/20 0.48
HIF1A Q16665 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
TSHR P16473 2/20 0.46
CYP2D6 P10635 2/20 0.45
KCNN4 O15554 1/20 0.43
ALDH1A1 P00352 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16753453 1.00 CYP1A2 (0.60) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL29613223 1.00 CYP1A2 (0.60) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL11715049 0.86 CYP1A2 (0.54) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL7255208 0.84 CYP1A2 (0.52) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL5552907 0.82 CYP1A2 (0.50) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL1817185 0.82 MAPT (0.63) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL27486196 0.82 ESR1 (0.50) CYP1A2MAPTKMT2ACYP2C19TSHR
SCHEMBL4742572 0.82 MEN1 (0.55) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL5473988 0.82 TSHR (0.46) CYP1A2MAPTKMT2ACYP2C19HDAC1
SCHEMBL17513419 0.80 HDAC3 (0.52) CYP1A2MAPTKMT2ACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107383365-A A kind of Semi-aromatic polyamide resin and preparation method thereof 无锡殷达尼龙有限公司 2017-11-24 CN claimed
CN-103113226-B Tert-butyl Methacrylate class monomer and polymkeric substance, preparation method and use SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2015-08-05 CN claimed
CN-103044493-B Acrylamide type monomer containing dicyclopentadienyl iron structure, as well as amphipathic polymer, preparation method and use thereof SHANGHAI INST ORGANIC CHEM 2015-04-29 CN claimed
CN-103113226-A Tert-butyl methacrylate monomer and polymer, synthesis method and application thereof SHANGHAI INST ORGANIC CHEM 2013-05-22 CN claimed
CN-103044493-A Acrylamide type monomer containing dicyclopentadienyl iron structure, as well as amphipathic polymer, preparation method and use thereof SHANGHAI INST ORGANIC CHEM 2013-04-17 CN claimed
EP-1072580-B1 PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID IHARA CHEMICAL IND CO (JP) 2010-12-01 EP claimed
CN-101492520-A Diblock copolymer containing full-fluorine cyclobutyl aryl aether block and uses thereof SHANGHAI INST ORGANIC CHEM (CN) 2009-07-29 CN claimed
US-7012138-B1 Chiral polysaccharide esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or for chiral chromatography UNIVERSITE DE DROIT D'ECONOMIE ET DES SCIENCES D'AIZ-MARSEILLE (FR) 2006-03-14 US claimed
EP-1135417-B1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY UNIV DROIT D ECONOMIE ET DES S (FR) 2003-06-25 EP claimed
US-6414186-B1 REACTING METHYLPHENYLACETIC ACID WITH CHLORINE GAS, IN INERT SOLVENT, UNDER IRRADIATION WITH LIGHT OR IN PRESENCE OF RADICAL INITIATOR IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2002-07-02 US claimed
EP-1135417-A1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY Universite De Droit, D'Economie et des Sciences D'Aix-Marseille (FR) 2001-09-26 EP claimed
EP-1072580-A1 PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID Ihara Nikkei Chemical Industry Co., Ltd. (JP) 2001-01-31 EP claimed
WO-2000032638-A1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY UNIVERSITE DE DROIT, D'ECONOMIE ET DES SCIENCES D'AIX-MARSEILLE (FR) 2000-06-08 WO claimed
JP-11302220-A None JP disclosed
US-20240024490-A1 BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES THE BROAD INSTITUTE, INC. 2024-01-25 US disclosed
US-11746178-B2 Polymer production method and radical polymerization initiating group-containing compound DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-09-05 US disclosed
US-4226806-A CHEMICAL INTERMEDIATES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1980-10-07 US disclosed
US-4148997-A 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1979-04-10 US disclosed
US-4093802-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-06-06 US disclosed
US-4031083-A Cephalosporin antibiotics YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024490-A1 BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES COASY, JMJD7, PTMS CYP1A2 2469/4885MAPT 3572/4885KMT2A 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.