Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744131 | 0.94 | ADRB2 (0.41) | ADRB2 | |
| SCHEMBL4738383 | 0.87 | ADRB2 (0.45) | ADRB2 | |
| SCHEMBL4742320 | 0.87 | ADRB2 (0.45) | ADRB2 | |
| SCHEMBL4740700 | 0.82 | ADRB2 (0.45) | ADRB2 | |
| SCHEMBL4784314 | 0.82 | ADRB2 (0.43) | ADRB2 | |
| SCHEMBL4738395 | 0.81 | ADRB2 (0.43) | ADRB2 | |
| SCHEMBL4744075 | 0.81 | ADRB2 (0.45) | ADRB2 | |
| SCHEMBL4784295 | 0.80 | ADRB2 (0.44) | ADRB2 | |
| SCHEMBL4789505 | 0.79 | ADRB2 (0.42) | ADRB2 | |
| SCHEMBL4742726 | 0.79 | ADRB2 (0.41) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096129-A1 | NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |