SCHEMBL4742756

SCHEMBL4742756

CC(=O)Oc1ccc(CCN)c2sc(=O)[nH]c12

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 14/20 0.37
NEK1 Q96PY6 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1190213 0.83 ADRB2 (0.43) ADRB2NEK1
SCHEMBL1803738 0.82 ADRB2 (0.34) ADRB2NEK1
Acetic Acid SCHEMBL4742751 0.79 ADRB2 (0.47) ADRB2
SCHEMBL2142589 0.79 ADRB2 (0.48) ADRB2
SCHEMBL1801843 0.79 ADRB2 (0.48) ADRB2
SCHEMBL4740762 0.76 ADRB2 (0.52) ADRB2
SCHEMBL13225809 0.76 HTR2A (0.39) ADRB2NEK1
Bromide SCHEMBL1683003 0.75 ADRB2 (0.51) ADRB2
Hydrochloric Acid SCHEMBL1179939 0.75 ADRB2 (0.51) ADRB2
SCHEMBL19301989 0.71 KDM4E (0.40) ADRB2NEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008096129-A1 NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS ARGENTA DISCOVERY LTD (GB) 2008-08-14 WO disclosed