Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714080 | 0.85 | KMT2A (0.74) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL6169266 | 0.85 | RAB9A (0.74) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL13789283 | 0.84 | KMT2A (1.00) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL13789346 | 0.84 | KMT2A (0.73) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL4743665 | 0.84 | KMT2A (0.73) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL4515370 | 0.83 | KMT2A (0.71) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL4574106 | 0.81 | MAPK10 (0.72) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL4743658 | 0.81 | NPC1 (0.68) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL23931980 | 0.79 | PTPN2 (0.72) | KMT2ANPC1MEN1RAB9AL3MBTL1 | |
| SCHEMBL16737094 | 0.78 | NPC1 (0.63) | KMT2ANPC1MEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092861-A1 | BICYCLIC DERIVATIVES AS EP4 AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-07 | — | — | WO | disclosed |