Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 11/20 | 0.42 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14446020 | 0.92 | PPARA (0.51) | PPARDPPARAPPARGASIC1 | |
| SCHEMBL14445956 | 0.86 | PPARA (0.46) | PPARDPPARAPPARG | |
| SCHEMBL5397707 | 0.86 | PPARA (0.45) | MAPTPPARDPPARAPPARGPOLB | |
| SCHEMBL5418507 | 0.86 | MAPT (0.45) | MAPTPPARDPPARAPPARGPOLB | |
| SCHEMBL4685213 | 0.83 | MAPT (0.41) | MAPTPPARDPPARAPPARGTP53 | |
| SCHEMBL4682592 | 0.83 | PPARA (0.41) | MAPTPPARDPPARAPPARGPOLB | |
| SCHEMBL4685126 | 0.82 | PPARA (0.43) | MAPTPPARDPPARAPPARGGCGR | |
| SCHEMBL4681908 | 0.82 | MAPT (0.46) | MAPTPPARDPPARAPPARGPOLB | |
| SCHEMBL14445976 | 0.80 | PPARA (0.41) | MAPTPPARDPPARAPPARGTP53 | |
| SCHEMBL4682146 | 0.78 | PPARA (0.45) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | claimed |
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |