Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.45 |
| ▸ | PPARG | P37231 | 15/20 | 0.45 |
| ▸ | PPARD | Q03181 | 14/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445990 | 0.92 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL14445956 | 0.90 | PPARA (0.46) | PPARAPPARGPPARDFBP1 | |
| SCHEMBL14445963 | 0.83 | PPARG (0.38) | PPARAPPARGPPARDAGERFBP1 | |
| SCHEMBL14445976 | 0.82 | PPARA (0.41) | PPARAPPARGPPARDFBP1 | |
| SCHEMBL14445985 | 0.80 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL4678572 | 0.80 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL5407750 | 0.79 | PPARD (0.39) | PPARAPPARGPPARDAGERFBP1 | |
| SCHEMBL4682719 | 0.79 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL4742857 | 0.78 | MAPT (0.42) | PPARAPPARGPPARD | |
| SCHEMBL4682143 | 0.78 | PPARD (0.41) | PPARAPPARGPPARDAGERFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | claimed |
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |