Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 3/20 | 0.65 |
| ▸ | PGF | P49763 | 3/20 | 0.65 |
| ▸ | FLT1 | P17948 | 2/20 | 0.65 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742863 | 1.00 | VEGFA (0.65) | VEGFAPGFFLT1PRKAA2ALPL | |
| SCHEMBL132838 | 0.83 | VEGFA (0.57) | VEGFAPGFFLT1PRKAA2ALPL | |
| SCHEMBL134913 | 0.83 | VEGFA (0.57) | VEGFAPGFFLT1PRKAA2ALPL | |
| SCHEMBL14468685 | 0.83 | VEGFA (0.57) | VEGFAPGFFLT1PRKAA2ALPL | |
| Geranin A SCHEMBL31186795 | 0.82 | VEGFA (0.89) | VEGFAPGFFLT1PRKAA2ALPL | |
| Geranin A SCHEMBL29554993 | 0.82 | VEGFA (0.89) | VEGFAPGFFLT1PRKAA2ALPL | |
| Geranin A SCHEMBL1689479 | 0.82 | VEGFA (0.89) | VEGFAPGFFLT1PRKAA2ALPL | |
| Geranin D SCHEMBL30414509 | 0.79 | VEGFA (0.85) | VEGFAPGFFLT1PRKAA2ALPL | |
| SCHEMBL14468690 | 0.78 | VEGFA (0.51) | VEGFAPGFFLT1PRKAA2ALPL | |
| SCHEMBL133791 | 0.78 | VEGFA (0.51) | VEGFAPGFFLT1PRKAA2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100977-A2 | CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS | N.V. ORGANON (NL) | 2008-08-21 | — | — | WO | disclosed |