Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.47 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | UBE2I | P63279 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082607 | 0.81 | MAPT (0.68) | MAPTHTT | |
| SCHEMBL10617 | 0.78 | DAO (0.60) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29370120 | 0.78 | DAO (0.60) | MAPTKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6506378 | 0.76 | DAO (0.58) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL27818462 | 0.76 | DAO (0.58) | MAPTKDM4EALDH1A1HPGD | |
| Formaldehyde SCHEMBL28001667 | 0.74 | DAO (0.56) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29563733 | 0.73 | MAPT (0.59) | MAPTKDM4EAPAF1ALDH1A1THRB | |
| SCHEMBL11829976 | 0.73 | MAPT (0.59) | MAPTKDM4EAPAF1ALDH1A1THRB | |
| Acetic Acid SCHEMBL28431508 | 0.72 | DAO (0.54) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28439712 | 0.72 | CA12 (0.67) | MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094203-A2 | POLAR ESTER PRODRUGS OF HETEROCYCLIC HYBRID ANTIBACTERIAL COMPOUNDS AND SALTS THEREOF | MICROBIOTIX, INC. (US) | 2008-08-07 | — | — | WO | disclosed |