Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485946 | 0.84 | ANPEP (0.42) | L3MBTL1MAPTALDH1A1POLBHPGD | |
| SCHEMBL19927629 | 0.84 | KCNA3 (0.39) | SMN1; SMN2ARG1ARG2LTA4H | |
| SCHEMBL11200711 | 0.84 | KEAP1 (0.38) | SMN1; SMN2 | |
| SCHEMBL2444748 | 0.82 | MAPT (0.43) | L3MBTL1MAPTALDH1A1POLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL31323938 | 0.81 | MAPT (0.42) | L3MBTL1MAPTALDH1A1POLBHTT | |
| Hydrochloric Acid SCHEMBL2444753 | 0.81 | MAPT (0.42) | L3MBTL1MAPTALDH1A1POLBHTT | |
| Hydrochloric Acid SCHEMBL2444744 | 0.81 | MAPT (0.42) | L3MBTL1MAPTALDH1A1POLBHTT | |
| SCHEMBL8798524 | 0.79 | KDM4E (0.34) | L3MBTL1ALDH1A1POLBSMN1; SMN2ACHE | |
| SCHEMBL18939466 | 0.79 | MAPT (0.38) | L3MBTL1MAPTALDH1A1POLBCYP1A2 | |
| SCHEMBL18939464 | 0.79 | MAPT (0.38) | L3MBTL1MAPTALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110351-A2 | USE OF (R) AND (S)-2-ARYL-PROPIONIC ACID DERIVATIVES AS ANTISEPTIC AGENTS | DOMPE' PHA.R.MA S.P.A. (IT) | 2008-09-18 | — | — | WO | disclosed |