Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786543 | 1.00 | CXCR4 (0.50) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL4739261 | 0.97 | CXCR4 (0.53) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL4786617 | 0.97 | CXCR4 (0.53) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL4786588 | 0.97 | CXCR4 (0.53) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL841438 | 0.97 | CXCR4 (0.53) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL10604006 | 0.97 | CXCR4 (0.53) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL11520861 | 0.97 | CXCR4 (0.52) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4641799 | 0.95 | CXCR4 (0.52) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL11523136 | 0.91 | CXCR4 (0.57) | CXCR4HRH4HRH3CXCL12ALDH1A1 | |
| SCHEMBL3695429 | 0.89 | CXCR4 (0.57) | CXCR4HRH4HRH3CXCL12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089010-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-07-24 | — | — | WO | disclosed |
| US-4555537-A | IMIDAZOLINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| EP-0039663-B1 | PROCESS FOR PREPARING CROSSLINKED SATURATED POLYMERS, AND THESE POLYMERS | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | disclosed |
| US-4424336-A | Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0012715-B1 | EPOXIDE RESIN/BETA-AMINOCROTONIC ACID DERIVATIVE COMPOSITIONS WHICH ARE HEAT CURABLE AND STABLE WHEN STORED, AND THE MANUFACTURE OF INSOLUBLE AND UNMELTABLE PLASTIC PRODUCTS THEREFROM | CIBA-GEIGY AG (CH) | 1982-12-08 | — | — | EP | disclosed |
| US-4360655-A | Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0008644-B1 | STORAGE-STABLE, THERMOSETTING MIXTURES BASED ON POLYIMIDES AND POLY-BETA-IMINOCROTONIC ACID NITRILES, AND THEIR USE | CIBA-GEIGY AG (CH) | 1982-04-21 | — | — | EP | disclosed |
| EP-0039663-A2 | Process for preparing crosslinked saturated polymers, and these polymers | CIBA-GEIGY AG (CH) | 1981-11-11 | — | — | EP | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4284752-A | Process for producing crosslinked unsaturated polymers by reaction of .beta. | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4247672-A | STORAGE STABILITY, MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
| EP-0012715-A1 | Epoxide resin/beta-aminocrotonic acid derivative compositions which are heat curable and stable when stored, and the manufacture of insoluble and unmeltable plastic products therefrom | CIBA-GEIGY AG (CH) | 1980-06-25 | — | — | EP | disclosed |
| EP-0008644-A1 | Storage-stable, thermosetting mixtures based on polyimides and poly-beta-iminocrotonic acid nitriles, and their use | CIBA-GEIGY AG (CH) | 1980-03-19 | — | — | EP | disclosed |