SCHEMBL11523136

SCHEMBL11523136

C(CNC1CCCC1)CNC1CCCC1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 12/20 0.57
CXCL12 P48061 1/20 0.57
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HRH4 Q9H3N8 4/20 0.44
HRH3 Q9Y5N1 4/20 0.44
RAD52 P43351 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17733777 0.97 CXCR4 (0.61) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL9417435 0.97 CXCR4 (0.61) CXCR4CXCL12KDM4EALDH1A1HRH4
Hydrochloric Acid SCHEMBL9714202 0.94 CXCR4 (0.59) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL4740704 0.94 CXCR4 (0.52) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL11520861 0.94 CXCR4 (0.52) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL4745523 0.92 CXCR4 (0.62) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL4786543 0.91 CXCR4 (0.50) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL4743282 0.91 CXCR4 (0.50) CXCR4CXCL12KDM4EALDH1A1HRH4
SCHEMBL10939737 0.89 CXCR4 (0.66) CXCR4CXCL12KDM4EHRH4HRH3
SCHEMBL4786617 0.88 CXCR4 (0.53) CXCR4CXCL12KDM4EALDH1A1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179469-A Preparation of amines UOP INC. (US) 1979-12-18 US disclosed