Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743288 | 0.99 | HRH3 (0.56) | MEN1KMT2AHRH3HRH1HRH4 | |
| SCHEMBL4743111 | 0.99 | HRH3 (0.56) | MEN1KMT2AHRH3HRH1HRH4 | |
| SCHEMBL4746716 | 0.91 | HRH3 (0.58) | MEN1KMT2AHRH3KCNA5 | |
| SCHEMBL4745334 | 0.89 | HRH3 (0.47) | MEN1KMT2AHRH3HRH4KCNA5 | |
| SCHEMBL4744719 | 0.89 | HRH3 (0.53) | MEN1KMT2AHRH3KCNA5DRD2 | |
| SCHEMBL4746230 | 0.89 | HRH3 (0.53) | MEN1KMT2AHRH3KCNA5DRD2 | |
| SCHEMBL4745366 | 0.89 | HRH4 (0.53) | MEN1KMT2AHRH3HRH1HRH4 | |
| SCHEMBL4744692 | 0.89 | KDM4E (0.51) | MEN1KMT2AHRH3HRH4KCNA5 | |
| SCHEMBL4743291 | 0.89 | HRH3 (0.48) | MEN1KMT2AHRH3HRH4KCNA5 | |
| SCHEMBL4743334 | 0.88 | HRH3 (0.55) | MEN1KMT2AHRH3KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |