Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743111 | 0.90 | HRH3 (0.56) | HRH4HRH3HRH1MEN1KMT2A | |
| SCHEMBL4743288 | 0.90 | HRH3 (0.56) | HRH4HRH3HRH1MEN1KMT2A | |
| SCHEMBL4743293 | 0.89 | MEN1 (0.56) | HRH4HRH3KDM4EALDH1A1DRD2 | |
| SCHEMBL4743291 | 0.86 | HRH3 (0.48) | HRH4HRH3HTR1ADRD2HTR2A | |
| SCHEMBL4745334 | 0.85 | HRH3 (0.47) | HRH4HRH3AVPR1BMEN1KMT2A | |
| SCHEMBL21026135 | 0.83 | HRH3 (0.55) | HRH3KDM4EALDH1A1HRH2HRH1 | |
| SCHEMBL4744692 | 0.83 | KDM4E (0.51) | HRH4HRH3KDM4ESMN1; SMN2POLB | |
| SCHEMBL4746716 | 0.82 | HRH3 (0.58) | HRH3MEN1KMT2A | |
| SCHEMBL4745400 | 0.81 | HTR1A (0.50) | HRH3HTR1ADRD2HTR2AAVPR1B | |
| SCHEMBL4744719 | 0.81 | HRH3 (0.53) | HRH3DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |