Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21483755 | 0.80 | TSHR (0.43) | L3MBTL1TDP1NPC1MAPTRAB9A | |
| SCHEMBL1427941 | 0.79 | TDP1 (0.54) | L3MBTL1TDP1APPSMN1; SMN2IDO1 | |
| SCHEMBL18745349 | 0.79 | L3MBTL1 (0.41) | L3MBTL1TDP1PPARGPPARAACACB | |
| SCHEMBL5284810 | 0.79 | L3MBTL1 (0.41) | L3MBTL1TDP1PPARGPPARAACACB | |
| SCHEMBL22986985 | 0.78 | PPARG (0.36) | PPARGPPARAACACBAPPIDO1 | |
| SCHEMBL4221559 | 0.78 | APP (0.46) | L3MBTL1APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4140242 | 0.77 | MEN1 (0.47) | TDP1PPARGPPARAACACBPPARD | |
| SCHEMBL2970086 | 0.77 | KDM4E (0.41) | PPARGPPARANPC1MAPTRAB9A | |
| SCHEMBL2464668 | 0.77 | PPARA (0.40) | PPARGPPARAACACBAPPIDO1 | |
| SCHEMBL1179919 | 0.75 | AGXT (0.50) | NPC1RAB9ASMN1; SMN2IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |