Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743355 | 1.00 | CHRNA7 (0.38) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL4744082 | 0.99 | KCNH2 (0.38) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL1109792 | 0.95 | KCNH2 (0.39) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL1109795 | 0.95 | KCNH2 (0.39) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| Bromide SCHEMBL2876849 | 0.95 | KCNH2 (0.38) | CHRNA7CYP19A1KCNH2CHRM2CHRM1 | |
| Bromide SCHEMBL2876843 | 0.95 | KCNH2 (0.38) | CHRNA7CYP19A1KCNH2CHRM2CHRM1 | |
| SCHEMBL1109774 | 0.94 | CHRNA7 (0.39) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL1109773 | 0.94 | CHRNA7 (0.39) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 | |
| SCHEMBL14101216 | 0.93 | LMNA (0.39) | CHRNA7CYP19A1KCNH2CHRM2CHRM1 | |
| SCHEMBL4742440 | 0.92 | CYP19A1 (0.39) | CHRNA7CYP19A1KCNH2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | claimed |
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |