Pyridine

Pyridine

SCHEMBL4743541

ClCc1ccc(Cl)cc1.c1ccncc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
LSS P48449 1/20 0.42
CYP19A1 P11511 3/20 0.41
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2B6 P20813 1/20 0.41
MAPK1 P28482 1/20 0.41
PKM P14618 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
IDO1 P14902 1/20 0.39
TSHR P16473 2/20 0.39
NAPRT Q6XQN6 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AKT1 P31749 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL2179529 0.84 TDP1 (0.45) CYP19A1CYP11B1CYP11B2TSHRNAPRT
(Chloromethyl)Benzene SCHEMBL27526930 0.82 TDP1 (0.43) CYP19A1CYP11B1CYP11B2TSHRNAPRT
Pyridine SCHEMBL10890647 0.82 TSHR (0.43) CYP19A1CYP11B1TSHRNAPRTTDP1
SCHEMBL120896 0.81
Methane SCHEMBL28356057 0.78 IDO1 (0.52) KDM4ECYP2A6IDO1
SCHEMBL4989141 0.78 IDO1 (0.52) KDM4ECYP2A6IDO1
Phosphine SCHEMBL4870393 0.78 IDO1 (0.52) KDM4ECYP2A6IDO1
SCHEMBL3986244 0.78 IDO1 (0.52) KDM4ECYP2A6IDO1
Hydrochloric Acid SCHEMBL11121998 0.78 IDO1 (0.52) KDM4ECYP2A6NPC1RAB9AIDO1
Pyridine SCHEMBL15644026 0.76 GAA (0.46) KDM4ECYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080201095-A1 Method for Calibrating an Analytical Instrument VERMILLION, INC. 2008-08-21 US disclosed
WO-2008100941-A2 A METHOD FOR CALIBRATING AN ANALYTICAL INSTRUMENT CORRELOGIC SYSTEMS INC. (US) 2008-08-21 WO disclosed