Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120896 | 0.97 | — | — | |
| SCHEMBL3986244 | 0.94 | IDO1 (0.52) | IDO1LMNACYP2A6TAAR1AGXT | |
| Phosphine SCHEMBL4870393 | 0.94 | IDO1 (0.52) | IDO1LMNACYP2A6TAAR1AGXT | |
| Methane SCHEMBL28356057 | 0.94 | IDO1 (0.52) | IDO1LMNACYP2A6TAAR1AGXT | |
| Hydrochloric Acid SCHEMBL11121998 | 0.94 | IDO1 (0.52) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL16663974 | 0.88 | TAAR1 (0.56) | IDO1LMNACYP2A6TAAR1AGXT | |
| Formaldehyde SCHEMBL27548647 | 0.88 | IDO1 (0.48) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL8992968 | 0.88 | IDO1 (0.48) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL2069301 | 0.88 | MAOB (0.54) | IDO1LMNACYP2A6TAAR1AGXT | |
| SCHEMBL27838456 | 0.86 | IDO1 (0.46) | IDO1LMNACYP2A6TAAR1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920771-A | Novel synthesis process of intermediate of novel oral medicine for overactive bladder | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-102649796-A | Preparation method for important intermediates of butoconazole nitrate | SICHUAN DIHON MEDICAL DEV CO LTD | 2012-08-29 | — | — | CN | claimed |
| CN-100548950-C | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2009-10-14 | — | — | CN | claimed |
| CN-1759084-A | Process for preparing esters and ethers of probucol and derivatives thereof | ATHEROGENICS INC (US) | 2006-04-12 | — | — | CN | claimed |
| CN-116396155-B | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 辽宁众辉生物科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113121322-B | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 辽宁众辉生物科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117402044-B | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 辽宁众辉生物科技有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-117402044-A | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 辽宁众辉生物科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116731083-A | Organic electroluminescent material and device | 环球展览公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-106946940-B | Organic electroluminescent material and device | 环球展览公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116396155-A | Synthesis method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 辽宁众辉生物科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-114920771-A | Novel synthesis process of intermediate of novel oral medicine for overactive bladder | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2004080463-A1 | HETEROCYCLIC KINASE INHIBITORS: METHODS OF USE AND SYNTHESIS | SCHERING CORPORATION (US) | 2004-09-23 | — | — | WO | disclosed |
| US-20030232891-A1 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2003-12-18 | — | — | US | disclosed |
| US-6653508-B2 | Use treating various medical conditions, including pain | GRUENENTHAL GMBH (DE) | 2003-11-25 | — | — | US | disclosed |
| CN-1441796-A | Cyclic substituted aminomethyl compounds and medicaments containing said compounds | GRUENENTHAL GMBH (DE) | 2003-09-10 | — | — | CN | disclosed |
| US-20020161262-A1 | 3-Amino-2-benzyl-1-phenylpropane derivatives | GRUENTENTHAL GMBH (DE) | 2002-10-31 | — | — | US | disclosed |
| CN-1255136-A | Substituted 4-arylmethylene-2-imino-2,3-dihydrothiazoles and derivatives and their pharmaceutical use | KNOLL AG (DE) | 2000-05-31 | — | — | CN | disclosed |
| US-5232916-A | Inhibitors of leukotriene synthesis | MERCK FROSST CANADA, INC. (CA) | 1993-08-03 | — | — | US | disclosed |
| US-5102881-A | Leukotriene biosynthesis inhibitor | MERCK FROSST CANADA, INC. (CA) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232891-A1 | Substituted C-cyclohexylmethylamine derivatives | CNR2, CNR1, HNMT | IDO1 1688/4885LMNA 1553/4885CYP2A6 376/4885 |
| US-20020161262-A1 | 3-Amino-2-benzyl-1-phenylpropane derivatives | PYGL, CYP11B2, GOT2 | IDO1 2440/4885LMNA 315/4885CYP2A6 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.