Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748208 | 1.00 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2POLB | |
| SCHEMBL4743930 | 1.00 | PPARG (0.53) | PPARGPPARACYP2C9KCNH2POLB | |
| SCHEMBL4744723 | 0.98 | PPARG (0.52) | PPARGPPARACYP2C9KCNH2POLB | |
| SCHEMBL4744720 | 0.98 | PPARG (0.52) | PPARGPPARACYP2C9KCNH2POLB | |
| SCHEMBL4744493 | 0.95 | PPARG (0.54) | PPARGPPARACYP2C9KCNH2KDR | |
| SCHEMBL4744498 | 0.95 | PPARG (0.54) | PPARGPPARACYP2C9KCNH2KDR | |
| SCHEMBL4787762 | 0.93 | PPARG (0.54) | PPARGPPARACYP2C9KCNH2ALDH1A1 | |
| SCHEMBL4787752 | 0.93 | PPARG (0.54) | PPARGPPARACYP2C9KCNH2ALDH1A1 | |
| SCHEMBL4744641 | 0.92 | PPARG (0.56) | PPARGPPARACYP2C9KCNH2POLB | |
| SCHEMBL4748381 | 0.92 | PPARG (0.56) | PPARGPPARACYP2C9KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |