SCHEMBL4744060

SCHEMBL4744060

Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCOc1ccc(C=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.62
PPARG P37231 16/20 0.62
PTPN1 P18031 1/20 0.53
PPARD Q03181 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9260216 0.89 PPARG (0.53) PPARAPPARGPTPN1PPARD
SCHEMBL4746588 0.88 PPARG (0.61) PPARAPPARGPPARD
SCHEMBL9096482 0.87 PPARG (0.58) PPARAPPARG
SCHEMBL4746469 0.85 PPARG (0.73) PPARAPPARGPPARD
SCHEMBL4744428 0.84 PPARA (0.60) PPARAPPARGPTPN1PPARD
SCHEMBL9521218 0.82 PPARA (0.49) PPARAPPARGPTPN1PPARD
SCHEMBL6696861 0.82 PPARA (0.81) PPARAPPARGPTPN1PPARD
SCHEMBL5112921 0.80 PPARA (0.75) PPARAPPARGPPARD
SCHEMBL6970285 0.80 PPARG (0.65) PPARAPPARGPPARD
SCHEMBL7162667 0.80 PPARG (0.60) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008117982-A1 HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME CRYSTAL GENOMICS, INC. (KR) 2008-10-02 WO disclosed