Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789126 | 0.82 | LTA4H (0.44) | TSHRMAPK1ALDH1A1MAPTKMT2A | |
| SCHEMBL7030622 | 0.77 | MAPK1 (0.46) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL15259639 | 0.76 | TSHR (0.46) | TSHRMAPK1CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL5875525 | 0.75 | MAPK1 (0.44) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL1021158 | 0.75 | GRM1 (0.49) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL11143559 | 0.75 | TSHR (0.50) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL5152927 | 0.75 | TSHR (0.50) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL230672 | 0.75 | MAPK1 (0.44) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL20629458 | 0.73 | CYP2D6 (0.42) | TSHRCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL11637695 | 0.72 | TSHR (0.52) | TSHRMAPK1CYP3A4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746178-B2 | Polymer production method and radical polymerization initiating group-containing compound | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2023-09-05 | — | — | US | disclosed |
| US-11746178-B2 | Polymer production method and radical polymerization initiating group-containing compound | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2023-09-05 | — | — | US | disclosed |
| US-10982033-B2 | Polymer production method and radical polymerization initiating group-containing compound | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2021-04-20 | — | — | US | disclosed |
| EP-3424960-A1 | POLYMER PRODUCTION METHOD AND RADICAL POLYMERIZATION INITIATING GROUP-CONTAINING COMPOUND | Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002619-A1 | POLYMER PRODUCTION METHOD AND RADICAL POLYMERIZATION INITIATING GROUP-CONTAINING COMPOUND | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| CN-100445375-C | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2008-12-24 | — | — | CN | disclosed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| CN-1753990-A | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2006-03-29 | — | — | CN | disclosed |
| US-6713629-B2 | PLANT FUNGICIDE | NIPPON SODA CO., LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| US-20030114649-A1 | 5,5-Disubstituted thiazolidine derivative pesticides | NIPPON SODA CO., LTD. | 2003-06-19 | — | — | US | disclosed |
| US-6476055-B1 | 5,5-disubstituted thiazolidine derivative pesticides | NIPPON SODA CO. LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| WO-2000037432-A1 | METHOD OF PRODUCING AROMATIC HALOGEN METHYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-29 | — | — | WO | disclosed |
| EP-0518412-B1 | Process for the alpha-chlorination of phenylacetonitriles | DSM NV (NL) | 1998-02-25 | — | — | EP | disclosed |
| US-5274165-A | Process for the α-chlorination of phenylacetonitriles | DSM N.V. (NL) | 1993-12-28 | — | — | US | disclosed |
| EP-0518412-A1 | Process for the alpha-chlorination of phenylacetonitriles | DSM N.V. (NL) | 1992-12-16 | — | — | EP | disclosed |
| EP-0140229-B1 | PROCESS FOR PRODUCING A HALOGEN-CONTAINING ETHYLBENZENE DERIVATIVE | Tosoh Corporation (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0137494-B1 | PROCESS FOR PRODUCING AN ALPHA-HALOGENO-BETA-PHENYLPROPIONIC ACID | Tosoh Corporation (JP) | 1988-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114649-A1 | 5,5-Disubstituted thiazolidine derivative pesticides | NAT1, DDT, TH | TSHR 28/4885CYP2D6 88/4885DRD2 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.