Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744265 | 1.00 | CD274 (0.59) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4745017 | 0.97 | CD274 (0.62) | CD274SPHK1POLBPPARAFFAR1 | |
| SCHEMBL4746708 | 0.93 | PPARA (0.56) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4746703 | 0.93 | PPARA (0.56) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4748486 | 0.91 | POLB (0.56) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4748382 | 0.91 | CD274 (0.53) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4748386 | 0.91 | CD274 (0.53) | CD274SPHK1POLBPPARAPTGIR | |
| SCHEMBL4743974 | 0.91 | PPARA (0.57) | CD274SPHK1POLBPPARAPPARG | |
| SCHEMBL4743964 | 0.91 | PPARA (0.57) | CD274SPHK1POLBPPARAPPARG | |
| SCHEMBL4787471 | 0.91 | CD274 (0.59) | CD274SPHK1POLBPPARAPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |