Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746703 | 1.00 | PPARA (0.56) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4787471 | 0.97 | CD274 (0.59) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4744260 | 0.93 | CD274 (0.59) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4744265 | 0.93 | CD274 (0.59) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4746750 | 0.92 | CD274 (0.50) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4746755 | 0.92 | CD274 (0.50) | PPARAPPARGCD274POLBSPHK1 | |
| SCHEMBL4745017 | 0.91 | CD274 (0.62) | PPARACD274POLBSPHK1MEN1 | |
| SCHEMBL4814177 | 0.90 | CD274 (0.51) | PPARAPPARGCD274SPHK1PDCD1 | |
| SCHEMBL4744018 | 0.90 | CD274 (0.51) | PPARAPPARGCD274SPHK1PDCD1 | |
| SCHEMBL4743964 | 0.90 | PPARA (0.57) | PPARAPPARGCD274POLBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |