⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL28395893 | 0.85 | TSHR (0.38) | — | |
| Sulfuric Acid SCHEMBL30034939 | 0.84 | CA5A (0.32) | — | |
| Sulfuric Acid SCHEMBL624266 | 0.84 | CA5A (0.32) | — | |
| Sulfuric Acid SCHEMBL28166939 | 0.82 | CA5A (0.30) | — | |
| Sulfuric Acid SCHEMBL28329764 | 0.82 | CA5A (0.30) | — | |
| Sulfuric Acid SCHEMBL29131540 | 0.82 | CA5A (0.30) | — | |
| Sulfamate SCHEMBL28005026 | 0.80 | CA1 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL2074324 | 0.77 | CES1 (0.31) | — | |
| Pyrazole SCHEMBL19615038 | 0.77 | — | — | |
| Sulfamide SCHEMBL28146364 | 0.75 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200317976-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2020-10-08 | — | — | US | claimed |
| EP-3458539-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | Monash University (AU) | 2019-03-27 | — | — | EP | claimed |
| WO-2017197438-A1 | NOVEL PHASE CHANGE MATERIAL AND METHODS OF USE | MONASH UNIVERSITY (AU) | 2017-11-23 | — | — | WO | claimed |
| CN-115996924-B | Substituted pyrazolyl compounds and methods of use thereof | 诺华医药股份公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20240383885-A1 | Compounds for Treating Cannabinoid Toxicity and Acute Cannabinoid Overdose | MAKSCIENTIFIC, LLC | 2024-11-21 | — | — | US | disclosed |
| CN-108368040-B | Diaryl monocyclic beta-lactam compounds and methods for their use in the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-111201021-B | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118496221-A | Chroman monocyclic beta-lactams for the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| US-12054480-B2 | Compounds for treating cannabinoid toxicity and acute cannabinoid overdose | MAKSCIENTIFIC, LLC (US) | 2024-08-06 | — | — | US | disclosed |
| US-11939325-B2 | Process for making biologically active compounds and intermediates thereof | MAKSCIENTIFIC, LLC (US) | 2024-03-26 | — | — | US | disclosed |
| CN-111171014-B | Monocyclolactam compounds and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-1882590-B | Fused heterocyclic compounds as serotonin receptor modulators | JANSSEN PHARMACEUTICA NV | 2014-03-05 | — | — | CN | disclosed |
| CN-101318961-B | Fused heterocyclic compound | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-101318961-A | Fused heterocyclic compound | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | CN | disclosed |
| CN-101318962-A | Fused heterocyclic compound | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | CN | disclosed |
| WO-2008101860-A1 | NOVEL PROCESS FOR THE PREPARATION OF 5-(4-CHLOROPHENYL)-1-(2,4-DICHLOROPHENYL)-4-METHYL-N-(PIPERIDIN-1-YL)PYRAZOLE-3-CARBOXAMIDE | SANDOZ AG (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-7358371-B2 | Process for the preparation of 1,5—carboxylic acid derivatives | SANOFI-AVENTIS (FR) | 2008-04-15 | — | — | US | disclosed |
| US-20070099978-A1 | Process for the preparation of 1,5 - carboxylic acid derivatives | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | disclosed |
| CN-1934089-A | Process for preparing 1, 5-diphenylpyrazole-carboxylic acid derivatives | SANOFI AVENTIS (FR) | 2007-03-21 | — | — | CN | disclosed |
| CN-1882590-A | Fused heterocyclic compounds as serotonin receptor modulators | JOHNSON & JOHNSON (BE) | 2006-12-20 | — | — | CN | disclosed |