Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742594 | 0.99 | HRH3 (0.56) | HRH3BCHEACHEKDM4EMEN1 | |
| SCHEMBL4746369 | 0.93 | HRH3 (0.49) | HRH3ACHEKDM4E | |
| SCHEMBL4744473 | 0.91 | HRH3 (0.50) | HRH3 | |
| SCHEMBL4744495 | 0.90 | HRH3 (0.51) | HRH3BCHEACHE | |
| SCHEMBL4742644 | 0.90 | HRH3 (0.52) | HRH3BCHEACHE | |
| SCHEMBL4742019 | 0.89 | HRH3 (0.49) | HRH3BCHEACHE | |
| SCHEMBL4744967 | 0.89 | HRH3 (0.49) | HRH3BCHEACHE | |
| SCHEMBL4742556 | 0.88 | HRH3 (0.54) | HRH3BCHEACHE | |
| SCHEMBL4744462 | 0.88 | HRH3 (0.51) | HRH3BCHEACHEMAOB | |
| SCHEMBL4745148 | 0.88 | HRH3 (0.48) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107321-A1 | HETEROCYCLIC COMPOUNDS USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |
| WO-2008107321-A1 | HETEROCYCLIC COMPOUNDS USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |