Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246101 | 0.90 | TBXA2R (0.39) | TBXAS1 | |
| SCHEMBL7246106 | 0.90 | TBXA2R (0.39) | TBXAS1 | |
| SCHEMBL4232318 | 0.88 | TBXAS1 (0.34) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4232327 | 0.88 | TBXAS1 (0.34) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4234872 | 0.86 | CYSLTR1 (0.36) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4234878 | 0.86 | CYSLTR1 (0.36) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4376517 | 0.84 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4376519 | 0.84 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4225688 | 0.84 | TBXA2R (0.33) | CYSLTR2CYSLTR1TBXAS1GLA | |
| SCHEMBL4225685 | 0.84 | TBXA2R (0.33) | CYSLTR2CYSLTR1TBXAS1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | claimed |