Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743654 | 1.00 | PPARA (0.57) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4743660 | 1.00 | PPARA (0.57) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4748385 | 0.93 | PPARG (0.58) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4748383 | 0.93 | PPARG (0.58) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4743913 | 0.92 | PPARA (0.54) | PPARAKDM4EPPARGPPARDKMT2A | |
| SCHEMBL4748466 | 0.92 | PPARA (0.54) | PPARAKDM4EPPARGPPARDKMT2A | |
| SCHEMBL4743905 | 0.92 | PPARA (0.54) | PPARAKDM4EPPARGPPARDKMT2A | |
| SCHEMBL4744730 | 0.91 | KDM4E (0.53) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4743960 | 0.91 | KDM4E (0.53) | PPARAKDM4EPPARGCD274PPARD | |
| SCHEMBL4744732 | 0.91 | KDM4E (0.53) | PPARAKDM4EPPARGCD274PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |