Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042456 | 0.93 | DRD2 (0.60) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8042459 | 0.93 | DRD2 (0.60) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8041665 | 0.82 | DRD2 (0.61) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8041667 | 0.82 | DRD2 (0.61) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8304330 | 0.82 | DRD2 (0.78) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL6505862 | 0.81 | DRD2 (0.71) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL13999713 | 0.81 | HTR2C (0.47) | DRD2MEN1KMT2ADRD4HTR2C | |
| SCHEMBL8042461 | 0.80 | DRD2 (0.59) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8041643 | 0.80 | DRD2 (0.59) | DRD2MEN1KMT2AATMGRM2 | |
| SCHEMBL8041645 | 0.80 | DRD2 (0.59) | DRD2MEN1KMT2AATMGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |