Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | GYS1 | P13807 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744667 | 1.00 | FFAR1 (0.58) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4746717 | 0.97 | CD274 (0.60) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4814177 | 0.92 | CD274 (0.51) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4744018 | 0.92 | CD274 (0.51) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4746563 | 0.91 | FFAR1 (0.55) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4748002 | 0.91 | CD274 (0.50) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4748001 | 0.91 | CD274 (0.50) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4744260 | 0.90 | CD274 (0.59) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4744265 | 0.90 | CD274 (0.59) | FFAR1CD274PDCD1PPARGPPARA | |
| SCHEMBL4747971 | 0.89 | HRH3 (0.47) | FFAR1CD274PDCD1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |