Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727341 | 0.82 | CHEK1 (0.41) | MEN1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL1461854 | 0.79 | MEN1 (0.47) | MEN1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL1031032 | 0.75 | CSNK2A1 (0.41) | MEN1KMT2AKDM4EFOSJUN | |
| SCHEMBL436102 | 0.75 | NPC1 (0.45) | MEN1KMT2AKDM4ENFKB1NFKB2 | |
| SCHEMBL27933640 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL8052677 | 0.75 | KDM4E (0.46) | MEN1KMT2AKDM4ECYP3A4CYP2E1 | |
| SCHEMBL219003 | 0.74 | CYP3A4 (0.45) | MEN1KMT2AKDM4ECYP3A4CYP2E1 | |
| SCHEMBL24786993 | 0.74 | FOS (0.49) | MEN1KMT2AKDM4EFOSJUN | |
| SCHEMBL1003749 | 0.73 | CYP19A1 (0.58) | MEN1KMT2AKDM4ENFKB1NFKB2 | |
| SCHEMBL28423248 | 0.72 | CYP3A4 (0.44) | MEN1KMT2AKDM4ECYP3A4CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110891-A2 | NEW HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED, (IN) | 2008-09-18 | — | — | WO | claimed |