Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525631 | 1.00 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL28231713 | 1.00 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL8718440 | 1.00 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL27579718 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL8718317 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL8722914 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL4001566 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL5322316 | 0.93 | PDE4A (0.54) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL28131184 | 0.91 | TDP1 (0.55) | LMNAL3MBTL1TDP1PDE4AKDM4E | |
| SCHEMBL2419821 | 0.85 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165564-A4 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | IND RES LTD (NZ) | 2003-01-22 | — | — | EP | claimed |
| EP-1165564-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2002-01-02 | — | — | EP | claimed |
| WO-2000061783-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2000-10-19 | — | — | WO | claimed |
| EP-2838535-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | Biocryst Pharmaceuticals, Inc. (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013158746-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2013-10-24 | — | — | WO | disclosed |
| WO-2008117046-A1 | PYRAZOLO [4, 3-D] PYRIMIDINES AS ANTIBACTERIAL COMPOUNDS | ASTRAZENECA AB (SE) | 2008-10-02 | — | — | WO | disclosed |
| EP-1165564-A4 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | IND RES LTD (NZ) | 2003-01-22 | — | — | EP | disclosed |
| EP-1023308-A4 | INHIBITORS OF NUCLEOSIDE METABOLISM | EINSTEIN COLL MED (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1165564-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000061783-A2 | PROCESS FOR PREPARING INHIBITORS OF NUCLEOSIDE METABOLISM | INDUSTRIAL RESEARCH LIMITED (NZ) | 2000-10-19 | — | — | WO | disclosed |
| EP-1023308-A1 | INHIBITORS OF NUCLEOSIDE METABOLISM | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019338-A1 | INHIBITORS OF NUCLEOSIDE METABOLISM | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-04-22 | — | — | WO | disclosed |