Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | RBP1 | P09455 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748724 | 0.97 | HTR7 (0.45) | HTR7KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL4748632 | 0.97 | HTR7 (0.43) | HTR7KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL4744148 | 0.92 | HTR7 (0.44) | HTR7KMT2ADRD4GRM2HTT | |
| SCHEMBL4748105 | 0.91 | HTR7 (0.41) | HTR7KMT2ADRD4GRM2HTT | |
| SCHEMBL4748288 | 0.89 | HTR7 (0.43) | HTR7KMT2ADRD4GRM2HSD11B1 | |
| SCHEMBL4823970 | 0.89 | HTR7 (0.45) | HTR7KMT2AMEN1DRD4GRM2 | |
| SCHEMBL4744984 | 0.89 | HTR7 (0.46) | HTR7KMT2ADRD4GRM2HTT | |
| SCHEMBL4748174 | 0.88 | HTR7 (0.42) | HTR7KMT2ADRD4GRM2HTT | |
| SCHEMBL4744953 | 0.88 | HTR7 (0.43) | HTR7KMT2AMEN1DRD4GRM2 | |
| SCHEMBL4746801 | 0.88 | HTR7 (0.46) | HTR7KMT2AMEN1DRD4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |