Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806556 | 0.90 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL9306760 | 0.90 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4742918 | 0.85 | CA9 (0.39) | ALDH1A1TSHRALOX5PTGESPPARG | |
| SCHEMBL4745479 | 0.83 | CYSLTR2 (0.37) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL9989723 | 0.83 | TSHR (0.38) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4746926 | 0.83 | PTPN11 (0.43) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL4746963 | 0.83 | PTPN11 (0.43) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL4747022 | 0.83 | PTPN11 (0.43) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL4745086 | 0.83 | PTPN11 (0.43) | ALDH1A1CYP3A4LMNAMEN1KMT2A | |
| SCHEMBL4743732 | 0.83 | PTPN11 (0.43) | ALDH1A1CYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113814-A1 | ORGANIC MOLYBDENUM COMPOUNDS, USE THEREOF AS FRICTION- MODIFIERS AND LUBRICATING COMPOSITIONS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-09-25 | — | — | WO | disclosed |
| US-5055211-A | Lubricating oil containing a mixed ligand metal complex and a metal thiophosphate | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-10-08 | — | — | US | disclosed |